Tag Archives: Calorie restriction mimetic

Berries for Your Brain!

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In 2004, Dr. David Sinclair and colleagues published a paper identifying STACS, sirtuin activating compounds.¬†Sirtuins are histone deacetylases that become active during caloric restriction. Two sirtuins SIRT1 and SIRT3¬† are associated with a host of caloric restriction benefits. The hope was that by identifying STACS that calorie restriction would lead to the discovery of calorie… read more