Primate Study Affirms: the CR Way Lifestyle can Extend Life and Protect against Age-related Disease

The CR Way logoOn April 1, primate researchers from the University of Wisconsin published a paper,* affirming that caloric restriction (CR) without malnutrition significantly improves age-related and all-cause survival in rhesus monkeys. The researchers point out that their data contrasts with findings in the widely reported 2012 National Institutes of Aging study, where CR was not seen to show a significant survival benefit. 

However, they emphasize an important point: The NIA control monkeys were effectively practicing modest calorie restriction because their food allotments were so well controlled.

*Colman, R. J. et al. Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys. Nat. Commun. 5:3557 doi: 10.1038/ncomms4557 (2014).

The results from the Wisconsin study support findings from a study of elderly Okinawans who followed calorie restriction for 60 years, limiting calories by only 11 percent: Their average lifespan is the longest, recorded in the world. They also experience less heart disease, cancer, diabetes, and Alzheimer’s disease. Their quality of life is better too: Many Okinawans who practice calorie restriction remain active well into their nineties and beyond. †

†Willcox BJ, Willcox DC, Todoriki H, et al. Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world’s longest-lived people and its potential impact on morbidity and life span. Ann N Y Acad Sci. 2007 Oct;1114:434-55.

“We see similar results,” says Paul McGlothin, president of, where thousands practice calorie restriction. “The CR Way encourages moderate calorie restriction, which improves quality of life and is easy to follow.

“I find it interesting that 5 monkeys in the NIA study – four calorie-restricted and one control monkey – did live exceptionally long lives: beyond 40 years of age, when the average age of death of monkeys in captivity is 26.

“A CR Way lifestyle has produced supercentenarians – such as the famed Jiroemon Kimura, who ate three small meals a day and is verified as the longest-lived man in history.”


Living the CR Waytm puts solid science to work to help you achieve extraordinary health in a friendly, holistic community where delicious meals and live, caring support are important. These are the objectives of the lifestyle:

  • Use calorie restriction science in health decisions: This often means not limiting calories if your BMI is below 24 or gaining weight if it is below 18.5).
  • Preserve adult stem cell health and activate your tissue repair capabilities.
  • Maintain DNA Stability.
  • Optimize your microbiome, i.e., the microbes in your gut (an emerging science).
  • Integrate your personal genomics into a lifestyle that fits your needs.
  • Develop a close relationship with a physician.

The CR Way is guided by scientists, doctors, and other world-leading experts who hold live teleconferences for members of LivingTheCRWay interest groups. Memberships support CR Way DNA HACR, a citizen science study open to all who want find out what they can do to slow or reverse aging.

Contact:           Paul McGlothin Paul@  914-762-8878

Meredith Averill          877-481-4841

Twitter:   Living the CR Way@pmcglothin


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