In 2004, Dr. David Sinclair and colleagues published a paper identifying STACS, sirtuin activating compounds. Sirtuins are histone deacetylases that become active during caloric restriction. Two sirtuins SIRT1 and SIRT3 are associated with a host of caloric restriction benefits. The hope was that by identifying STACS that calorie restriction would lead to the discovery of calorie… read more
Tag Archives: histone deacetylases
Vinegar and Calorie Restriction Don’t Mix
One of our members recently asked why the CR Way no longer recommends vinegar. All CR Way suggestions have a fundamental goal of helping you live longer and better. That must include activation of the 7 sirtuin genes, which play vital roles in many aspects of life extension. Here, for example, is a press article… read more