Tag Archives: histone deacetylases

Berries for Your Brain!

In 2004, Dr. David Sinclair and colleagues published a paper identifying STACS, sirtuin activating compounds. Sirtuins are histone deacetylases that become active during caloric restriction. Two sirtuins SIRT1 and SIRT3  are associated with a host of caloric restriction benefits. The hope was that by identifying STACS that calorie restriction would lead to the discovery of calorie… read more

Vinegar and Calorie Restriction Don’t Mix

One of our members recently asked why the CR Way no longer recommends vinegar. All CR Way suggestions have a fundamental goal of  helping you live longer and better. That must include activation of the 7 sirtuin genes, which play vital roles in many aspects of life extension. Here, for example, is a press article… read more